Author Archives: Bob Nellis

Mayo Validates Zebrafish as Nicotine Research Model

Journalists:  For links to web-video and audio files, see the bottom of this post.
Mayo Clinic researchers and collaborators have validated the zebrafish as a functional model for nicotine addiction research. The findings appear in the Proceedings of the National Academy of Sciences (PNAS). The zebrafish is valuable because it is easy  to study and exhibits [...]

Mayo Clinic Tests Non-Surgical, Endoscopic Ulcer Repair

Mayo Clinic surgical researchers are reporting a 93 percent success rate in recent animal tests of endoscopic repair of perforated ulcers. The goal is to advance the use of an endoscope — which allows access to organs through natural openings, such as the mouth —
for a less invasive alternative to laparoscopic techniques (surgery performed through [...]

Novel Breast Tissue Feature may Predict Woman’s Cancer Risk

Mayo Clinic researchers have found that certain structural features within breast tissue can indicate a woman’s individual cancer risk. The findings appear online today in the Journal of Clinical Oncology.
The study shows that acini (AS-ih-nye), the small milk-producing elements in breast lobules, can be counted in sample biopsies. The percentage of acini present per lobule [...]

Mayo Clinic Researchers Find More Than Just Fatigue Behind Medical Errors By Residents

Journalists: For links to web-video and audio files, see the bottom of this post.
Mayo Clinic researchers report that distress and fatigue among medical residents are independent contributors to self-perceived medical errors. The findings appear today in the Journal of the American Medical Association (JAMA).
“We looked at distress and fatigue together and found that both factors [...]

Induced Pluripotent Stem Cells Repair Heart, Mayo Clinic Study Shows

In a proof-of-concept study, Mayo Clinic investigators have demonstrated that induced pluripotent stem (iPS) cells can be used to treat heart disease. iPS cells are stem cells converted from adult cells. In this study, the researchers reprogrammed ordinary fibroblasts, cells that contribute to scars such as those resulting from a heart attack, converting them into [...]

Mayo Genomic Discovery: Protecting Kidney Function During Heart Failure

Mayo Clinic cardiology researchers have found a peptide that helps preserve and improve kidney function during heart failure, without affecting blood pressure. Earlier variations of this peptide caused blood pressure to drop limiting the potential benefits to the kidneys. The findings appear in the current Proceedings of the National Academy of Sciences.
“Heart failure itself and [...]

Bariatric Surgery Increases Broken Bone Risk

Mayo Clinic researchers are reporting that persons who undergo bariatric surgery may have a greater chance of experiencing broken bones, especially in their hands and feet. The study is based on a review of nearly 100 surgical cases at Mayo spanning 21 years and is being presented today at the Endocrinology Society Annual Meeting in [...]

Mayo Clinic Alzheimer’s Expert in HBO Online Production

Ronald Petersen, M.D., Ph.D., head of Mayo’s Alzheimer’s Disease Research Center, is featured in an HBO-produced feature on Mild Cognitive Impairment. Dr. Petersen, a national expert in dementias, is focused on finding ways to make the earliest possible diagnoses for MCI. Dr. Petersen diagnosed President Ronald Reagan’s Alzheimer’s disease. Here’s a sampling:
[...]

Green Tea may hold future for Leukemia Treatment

Mayo Clinic researchers are reporting positive results in early leukemia clinical trials using the chemical epigallocatechin gallate (EGCG), an active ingredient in green tea. The trial determined that patients with chronic lymphocytic leukemia (CLL) can tolerate the chemical fairly well when high doses are administered in capsule form and that lymphocyte count was reduced in [...]

Patients to Pests

Mayo Clinic and the University of Minnesota researchers have been collaborating on medical research for over five years as part of the Minnesota Partnership for Biotechnology and Medical Genomics. Now they’ve gone from humans to bugs. Investigators have discovered a way to create a human-safe pesticide aimed specifically at aphids that destroy soybeans and other [...]