Researchers at Mayo Clinic’s campus in Jacksonville and Virginia Tech in Blacksburg, Va., through their technology commercialization efforts, have licensed compounds to Astra Zeneca for potential new drug therapies to treat depression. The collaboration advances both the development of novel compounds and supports ongoing research by Mayo and Virginia Tech in the area of triple [...]
Findings from a new study prompt Mayo Clinic researchers to recommend CYP2D6 gene testing for postmenopausal women about to begin tamoxifen therapy. New data confirms that women with an inherited deficiency in the CYP2D6 gene important for the metabolism of tamoxifen have a nearly 4-fold higher risk of early breast cancer recurrence compared to women [...]
Mayo Clinic researchers have discovered that a chemical known as endoxifen appears to be the primary metabolite responsible for the effectiveness of tamoxifen in treating breast cancer, and that it works against cancer in an entirely unexpected way.
Their study, presented at the 31st annual San Antonio Breast Cancer Symposium, finds that, in contrast to the [...]
Mayo Clinic researchers have studied the largest group of patients to date to understand the risk of non-cardiac elective surgery for those who have cardiac stents. The two papers, along with an editorial, are in the current issue of Anesthesiology.
The research indicates that patients who have cardiac stents placed in arteries should wait before having [...]
John Heit, M.D., a cardiovascular physician at Mayo Clinic, received today a $1.1 million grant from the National Institutes of Health for its Genes, Environment and Health Initiative. Dr. Heit’s grant will be used to study the genome-wide association of venous thrombosis (blood clots in the veins).
Deep vein thrombosis is a blood clot in a [...]
Updated 9/18/08
A Deep Brain Stimulation (DBS) consortium of Mayo Clinic physicians, scientists and engineers developed a wireless sensor that can detect chemical activity in the brain. The new system, called a wireless instantaneous neurotransmitter concentration sensor (WINCS), is connected to an electrode that will be surgically implanted in the brain to provide real-time measurements of [...]
Even though 30,000 patients in the United States undergo lung surgery each year, no standard criteria exist to measure the quality of their care. In the current issue of The Annals of Thoracic Surgery, Mayo Clinic surgeons have proposed a system of lung surgery quality indicators for surgeons and the public as a method to [...]
Mayo Clinic researchers have developed an improved statistical model that could help ensure that the sickest patients receive liver transplants first.
Researchers found that including serum sodium concentration in the statistical model now used could reduce by 7 percent the number of patients (as many as 50 people) who die each year while waiting for a [...]
A new Mayo Clinic study found that individuals with earlier onset, longer duration and greater severity of diabetes appear to be more likely to have mild cognitive impairment. Mild cognitive impairment (MCI) is a transitional stage between normal aging and the earliest features of Alzheimer’s disease.
“There is an obesity epidemic in this country. Since obesity [...]
ROCHESTER, Minn. — The world record pace for the marathon continues to improve for both men and women. For men, the record pace for the marathon is now about as fast as the record pace for the 10,000-meter just after WWII. Today, champion athletes are running more than four times farther at speeds of well [...]
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