Journalists: For links to video and audio files, see the bottom of this post.
Children exposed to two or more anesthetics before age 3 had more than double the incidence of ADHD than children who had no exposure, says David Warner, M.D., a Mayo Clinic pediatric anesthesiologist and investigator on the study. The findings are published in the Feb. 2 edition of Mayo Clinic Proceedings.
The study utilized results of an existing epidemiological study that looked at educational records of children born between 1976 and 1982 in Rochester, Minn., and determined those who developed some form of learning disability or ADHD.
Among 341 cases of ADHD in those younger than 19, researchers traced medical records in the Rochester Epidemiology Project, a decades-long database of all patient care in Olmsted County, Minn., looking for exposure to anesthesia and surgery before age 3.
Children who had no exposure to anesthesia and surgery had ADHD at a rate of 7.3 percent. The rate after a single exposure to anesthesia and surgery was approximately the same. For children who had two or more exposures to anesthesia and surgery, the rate of ADHD was 17.9 percent, even after researchers adjusted for other factors, including gestational age, sex, birth weight and comorbid health conditions.
The results of the study, however, do not definitively mean that anesthesia causes ADHD, Dr. Warner says.
“This is an observational study,” he says. “A wide range of other factors might be responsible for the higher frequency of ADHD in children with multiple exposures.
The findings certainly do suggest that further investigation into this area is warranted, and investigators at Mayo Clinic and elsewhere are actively pursuing these studies.”
For more information, a copy of the study or to schedule an interview with one of the investigators, contact firstname.lastname@example.org or call 507-284-5005.
Journalists: The following video and audio clips with Dr. Warner are available for download and use in your stories.
Below is a link to an edited youtube video with Dr. Warner that you can embed with your stories.