Journalists: For links to video and audio files, see the bottom of this post.
Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa, a Mayo Clinic researcher has shown. Steroids attached to the dendrimers targeted only damage-causing cells, leaving the rest of eye unaffected and preserving vision.
“We’ve developed an intracellular, sustained-release drug delivery system,” says lead author Raymond Iezzi, M.D., a Mayo Clinic ophthalmologist. Dr. Iezzi conducted the research in part at Wayne State University’s Kresge Eye Institute, and collaborated with scientists from Wayne State’s College of Engineering and Ligon Research Center of Vision. The study, performed in rats, appears in the journal Biomaterials.
Journalists: The following video and audio clips with Dr. Iezzi explaining the process are available for download and use in your stories.
Video: MP4
Audio: MP3
Below is a link to a youtube video with Dr. Iezzi that you can embed with your stories.
i am suffering from retinitis pigmentosa . How much time it takes for human trials please let me know because my vision is worse….awaiting for ur reply.
thanks
Thank you for your post, we cannot diagnose conditions, provide second opinions or make specific treatment recommendations through this correspondence. If you would like to seek help from Mayo Clinic, please call one of our appointment offices. Arizona: 480-301-1735 Florida: 904-953-0853 Minnesota: 507-284-2511. I am also attaching a link with more information on retinitis pigmentosa, http://www.riversideonline.com/health_reference/Eye/AN01200.cfm
I have been diagnosed with CRVO in both eyes and, now, a uveitis specialist believes the cause is sarcoidosis. I am presently taking 20mg of prednisone to see if the swelling around the optic nerve in my left eye will come down. Is there a possibility of the treatment discussed in the article being effective for my condition?
I am a pharmacist and unfortunatly suffering from retinal pigmentosa .I consult too many doctor in india ,no one start the treatment, all of say you have no problem but i know the my problem. please give right suggetion regarding the retinal pigmentosa
thank
I am an optometrist in Denver and have a patient who has been diagnosed with a vitelliform version of dry macular degeneration. No neovascularization detected. There is central choroidal atrophy. My question would be whether this form of macular degeneration lends itself to nanoparticle therapy?. If there is a possibility, what is the next step in investigating possible treatment?
Thank you
I am 47 years old and suffering from eyesight problem since last 10 years.In 2007 I had a complete eye check up.I had an electroretinography(ERG) test done.The findings reveal abnormal scotopic and photopic ERG response,compatible with rod-cone dystrophy.
1. Scotopic ERG: Low amplitude response of 80 uv
2. Photopic Erg: Normal amplitude and latency of photopic ERG”a” wave but grossly reduced”b” wave.
Now after 5 years my condition has become worse.doctors in india say there is no treatment for this problem…awaiting for ur reply