Two janus kinase (JAK) inhibitors are substantially improving treatment of myelofibrosis in patients, say Mayo Clinic researchers who are presenting results of several clinical trials at the 52nd annual meeting of the American Society of Hematology (ASH) Dec. 4–7 in Orlando.
Their findings suggest that both drugs, CYT387 and TG101348, effectively reduce spleen size and alleviate constitutional symptoms, major symptoms of this disorder, but that each have unique benefits.
Below, principal researcher Ayalew Tefferi, M.D., and lead investigator Animesh Pardanani, Ph.D., further discuss these studies.
Below is a link to an edited youtube video with Dr. Pardanani and Dr. Tefferi that you can embed with your stories. It will be made public when the embargo lifts.
WOULD BE INTERESTED TO LEARN MORE ABOUT THESE TRIALS AND IF THEY ENROLL. HAVE A FAMILY MEMBER THAT NEEDS HELP.
Your request has been referred to Dr. Tefferi.
In answer to your question below, I am told that we currently do not have any JAK2 inhibitor studies open for accrual.
Here is a link to check for clinical trials here at Mayo: http://clinicaltrials.mayo.edu/
Thank you for the interest in research at Mayo Clinic. Currently, we have 3 myelofibrosis studies underway and enrolling participants. We also have a family study for blood cancers.
Please contact the Mayo Clinic Cancer Center Clinical Trials Referral Office at (507-538-7623) for additional study information. Staff will gather preliminary contact information and the phone call will be returned in a day or two.
We are always glad to assist with information on the latest cancer research. Hope this is helpful.
Toni Kay Mangskau
Mayo Clinic Cancer Center
Clinical Trials Referral Coordinator
Hello!
One of my family member was just diagnosed with Myelofibrosis and I would like to get more information on how to apply for your clinical trials. Thank you so much
Hello. We are sorry to hear about your family member’s recent diagnosis of myelofibrosis. The following link will give you more information on available clinical trials at Mayo Clinic. Thank you for your question!