Comments on: Crohn’s Disease Study on Infliximab, Azathioprine

By: mayoclinic

mayoclinic — Mon, 24 Oct 2011 19:46:18 +0000

Susan, Unfortunately, we cannot diagnose conditions, provide second opinions or make specific treatment recommendations through this correspondence. If you would like to seek help for your daughter from Mayo Clinic, please call one of our appointment offices. The numbers can be found at this link: http://www.mayoclinic.org/patientinfo/appointments.html

By: Joyce Groenke

Joyce Groenke — Fri, 21 Oct 2011 14:39:30 +0000

We have received your comment and have forwarded it for reply.

By: susan miller

susan miller — Fri, 21 Oct 2011 13:22:45 +0000

my daughter has had crohns since the age of 10 .Had her large bowel removed 10 years ago got ileostmoy.Went on to infliximab in August 209 had 3 months of it starting to go deaf but doctor want except its through infliximab.when she had her ileostomoy they left 5cm of bowel attached to rectum since then she had vaginal discharge which smelled from june last year210.Had operation in january because bowel had gone into vagina had second op in March to take muscal out of leg to repair rectum and vagina which had broken down .Now they want her to go back on infliximab which made her deaf and dont know what to do she was told by one doctor to come of it or she would be stone deaf she has two earing aids what would you do

By: orla

orla — Mon, 08 Nov 2010 13:01:56 +0000

My daughter was,as a last resort,instead of surgery,put on infliximab,the other day,she had a very bad reaction to it.the doctor said it was a phycotic episode,only I was with her,she could have harmed herself by accident. I know, not everyone reacts the same,but it was so bad,it lasted a day and a night,next morning she was fine,I don’t know whats going to happen now,she has heard so many scare stories about surgery,(shes 28 and was born premature,26 weeks)and is putting off surgery.she is in hospital at the moment,she had ab-sis on her bowel.

By: Amy

Amy — Mon, 24 May 2010 13:55:53 +0000

Experts in our Mayo Clinic Inflammatory Bowel Disease Clinic at 507-538-3270 (Minnesota) can help with your questions. Also, please visit our web site for more information on appointments: http://www.mayoclinic.org/ibd/

By: shirley nowak

shirley nowak — Wed, 19 May 2010 22:22:06 +0000

i have had chrones diease for over 30 years i am on humuria , my dr. retired and i need coloncopy and i am deathly afried. any one with help please wright.

By: Merri Meade

Merri Meade — Fri, 02 Apr 2010 17:07:39 +0000

I have had Crohn’s Disease for 20 years. I’ve had 3 surgeries on my small and large intestines and one fiscula. I have been sick for so long and it never stops permanently. Right now I take Remicade treatments 15mg every 8 weeks. It does help me to have a more “normal” life, but I still have 2 or 3 days at a time when the Crohn’s still flares up and I am in the bed for 2 or 3 days at a time. My doctor informed me that I cannot have anymore surguries because I do not have enough intestine left to take out without having to have a coloscopy (a bag). This Disease is very depressing for me. I have missed so much out of my life, my diet is down to almost nothing and I have allienated myself from all my friends. Just being sick soo much. Really no one wants to here that your feeling well all the time, eventually they get tired of hearing about it, and I don’t blame them. My husband of 10 years is supportive but tired of me getting sick on a regular basis. I normally don’t eat red meat due to my Chrohn’s, but I made a meatloaf and the textures was soft, I had one piece and I was sick for 4 days. I’m sure a lot of people can relate to way I’m saying.

By: Amy Tieder

Amy Tieder — Wed, 24 Mar 2010 18:57:19 +0000

Crohn’s disease usually recurs if untreated and requires long term suppressive maintenance therapy. Drugs that contain mesalamine (like Asacol) in many instances do not adequately suppress the Crohn’s disease. Immunosuppressive medications like azathioprine and 6-mercaptopurine and biologic drugs like infliximab (Remicade), adalimumab (Humira), and certolizumab pegol (Cimzia) can suppress Crohn’s disease and maintain remission. They have small but real risks of serious infection and lymphoma. The risks of the drug side effects have to be considered against the risk of recurrent Crohn’s disease (which can lead to bowel blockage, fistulas, and abscess which is a form of serious infection). For many patients, the benefits of suppressing the Crohn’s disease with these medications outweighs the risks from the medications. This benefit risk decision is an individual and personal decision for each patient, and is best made in the context of a one on one visit with their physician.

William J. Sandborn, M.D.

By: Marge Wheat

Marge Wheat — Tue, 23 Mar 2010 23:57:36 +0000

I had surgery for a blockage. They had to take out a foot of my small intestine and told me I had Crohns disease. I am now on Asacol and still have some pain. The doctor mentioned Remicade which can cause lymphoma. My husband suffered six and half years from lymphoma which he was treated at Mayo clinic in Rochester.He passed away in 2008. Because of that it scares me to even think of trying Remicade. I have read some of the concerns on this sight which I can relate to. I am getting myself so worked up over this and I know that is not good either. Any answers or help would be appreciated.

By: Amy Tieder

Amy Tieder — Mon, 15 Feb 2010 18:31:33 +0000

I would recommend you call the Mayo Clinic Inflammatory Bowel Disease Clinic at 507-538-3270 (Minnesota) or visit our web site for more information on appointments: http://www.mayoclinic.org/ibd/