Leptin, a hormone that regulates appetite, appears to be associated with cardiovascular disease, say researchers at Mayo Clinic. According to findings published in Nature Clinical Practice Cardiovascular Medicine, adults with high levels of leptin in their blood appear to have a higher risk for developing cardiovascular disease than do those with lower leptin levels.
Mayo Clinic cardiologists Abel Romero-Corral, M.D., M. Sc. and Virend Somers, M.D., Ph.D., also found that those with high levels of both leptin and C-reactive protein may be at the greatest risk for having cardiovascular disease. High levels of C-reactive protein alone have previously been thought to be an important marker of heart disease risk.
Dr. Somers explains the study’s findings.
Dr. Somers emphasizes that it is still early, and that more research is needed to determine the association between leptin, C-reactive protein and cardiovascular disease.